Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
15. 有趣的巧合。环球影业是题材最具多样性的制片公司之一，它发行了《生活残骸》，也发行了《冲出康普顿》，还有《泰迪熊2》(Ted 2)。环球影业的女导演也是最多的，12月初，它占据了今年24%的市场份额。
Spielman was sifting through dirt at the Emek Tzurim national park on the slopes of the Mount of Olives in Jerusalem when she noticed the small rectangular object.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
陆金所是最大的一家。它是中国平安保险(Ping An Insurance)的子公司，平安也是陆金所最大的股东。
10. Economics is killing the economy, but like coke addicts we won't stop
The ministry expects consumption to remain a strong force driving economic growth this year.
Trends and targets in antiviral phototherapy
瑞士洛桑国际管理发展学院(IMD)和西班牙Iese商学院(Iese Business School)稳坐英国《金融时报》两份高管教育榜单榜首。英国《金融时报》2017年高管教育排行榜开放招生课程和定制课程两份排名的头两名，均由这两所学校包揽。
来自的日本的Kazutaka Kurihara和 Koji Tsukada被授予声学奖，以奖励他们发明的“沉默枪”——这是一种可以打断人说话的机器，其原理是让说话者听到自己稍有延迟的说话声音，这个装置可以治疗在特定演讲中容易结巴的人。
The studio says it has taken the step because the boy declined to remove a YouTube video he published which promoted how to use the software.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Best film and best director. Surprisingly, Nolan has never received a directing nomination from the Academy.
Novel biosensing methodologies for ultrasensitive detection of viruses
The data was released by the National Bureau of Statistics on its website, saying the growth rate rebounded for the first time after a four-year straight drop.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
The private Facebook group chat that led to offers of admission being rescinded was named, at one point, "Harvard memes for horny bourgeois teens", the Crimson reported.
Vocal event of the year: "The Only Way I Know," Eric Church, Luke Bryan and Jason Aldean
ACE2 as a potential therapeutic target for pandemic COVID-19
排行榜上前7所院校还是老面孔。澳大利亚新南威尔士大学商学院(UNSW Business School of Australia)澳大利亚管理研究生院(AGSM)首次上榜，排在第八位。
Diagnostic technologies for COVID-19: a review
People who are skeptical about this argument just need look at smartphones and personal computers, which have served as the technological driving force of the past century.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
"If it (transforming the economic development mode) only results in empty talk instead of being implemented, then economic development cannot be promoted in a sound and rapid way, and may even not be sustained." LI YIZHONG, member of the CPPCC National Committee and former minister of industry and information technology
Guo Jingjing's alleged romance with Kenneth Fok, the grandson of late Hong Kong tycoon Henry Fok, has captured the imagination of a country that seems to have become as interested in the private lives of its athletes as in their athletic performances.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
But industry watchers say that view misses an area where China goes toe-to-toe with Western rivals in innovation: extra features that make the Chinese version more interactive and more interesting to use.
The programme is ranked second for career progress three years after graduation. Tiemba’s graduates number only about 250 so far, making them an elite group.— LaurentOrtmans
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
For the first time in six years, a new challenger has topped the FT’s ranking of executive MBA programmes.
Influenza neuraminidase: A druggable target for natural products
Companies do have black lists. It's not written down anywhere but it's a list of people they'd be happy to get rid of if the opportunity arises. If you feel invisible, if you're getting bad assignments, if your boss is ignoring you, or if they move your office, you're probably on it.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
If you've got children, I understand that this isn't always possible. Children should always come first. But if you don't show up for your classes, you're not getting that education we discussed in No. 1.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
People with Type A personalities are often high-achieving "workaholics". They push themselves with deadlines, and hate both delays and ambivalence. People with Type A personalities experience more job-related stress and less job satisfaction.
The Atlanta-based group expects sales, adjusted for acquisitions, divestitures and currency fluctuations, to rise 3 per cent, compared with its earlier forecast of between 4 per cent and 5 per cent.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Best Companies rank: 25
Inhibition of SARS coronavirus helicase by bismuth complexes
gala＝milk牛奶，milky way＝银河系以xy结尾的只有4个单词，xy表示交织在一起，象坐标线一样，银河系也象星星交织在一起。参：neodoxy（n 新学说；新见解）；orthodoxy（adj 正统的）；heterodoxy（n 非正统；异说）
The magazine also notes that he gave $66 million to his presidential campaign and paid $25 million to settle a lawsuit related to Trump University.
Elsewhere, Dua Lipa, who was up for three gongs, took home the Best New Artist award. While Harry Styles might have a reputation for being one of the most stylish members of One Direction, the Sign of the Times singer had his crown stolen by surprise MTV EMAs newcomer and former band mate, ZAYN.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
But he told Washington's Observer-Reporter paper that he was keen to read it as it was "a testament of the sincerity, interest and innocence of that time".
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
“This has been a miserable year for EM,” said Paul McNamara, investment director of emerging markets at GAM, the Swiss fund house. “There has been a steady bleed out of assets and no one is certain what shape the market might be in this time next week.”
Like many child stars, Maddie speaks of being old before her time.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
7. Smart cookie oven
“My manifesto with Summly was to get our technology into as many users’ hands as possible,” Mr D’Aloisio said, pointing to Yahoo’s hundreds of millions of users. “With Yahoo’s reputation as a content portal, we have an opportunity to fundamentally change the way content is consumed.”
8. Software engineer
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Effective bosses must be effective decision makers. He or she cannot vacillate over every tiny decision. Being able to make decisions quickly and decisively — and then take responsibility for the outcome (see number 2) — is an important business skill, especially when managing others。
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
The Portuguese school has risen 31 places over the past two years since its International Master in Management course was first included in the ranking.
Coca-Cola said that the consumer slowdown in China had hit sales, and weaker demand was forcing it to drive down inventory.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
2. Take baby steps.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Gitanjali won a $25,000 prize for scooping the top award.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
I'm only a child yet I know we are all part of a family, five billion strong, in fact, 30 million species strong and we all share the same air, water and soil -- borders and governments will never change that. 我只是一个小孩，但我知道我们都是一个大家庭的成员，超过60亿人的大家庭，以及超过三千万物种的大家庭，政府和国界永远都无法改变这个事实。
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
"In the aftermath of recessions, there's always a period of jobless recovery," says John Challenger, CEO of global outplacement firm Challenger Gray & Christmas. "We're certainly not optimistic about seeing much improvement in the unemployment rate in 2010."
Manufacturing and sectors like leisure and hospitality should keep creating jobs. America's factories drove the early part of the U.S. recovery and, although growth has slowed, they should continue to add workers selectively. After adding about 9,000 jobs a month in 2010, manufacturing has added about 16,000 jobs a month so far this year. Slowdowns in Europe, Japan and fast-growing China have hurt global trade flows. But lately, more corporate executives are realizing that making things in the U.S. has benefits over, say, China. Meanwhile, the leisure sector, including restaurants, has been a reliable source of job growth all year.[qh]
In contrast, the average unit price of emerging market exports has been falling in year-on-year terms pretty much since mid-2012, hitting a year-on-year decline of 16.4 per cent in February 2016.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
New York City, now ranked seventh, has gone up 15 places since last year. It has seen a big jump in costs over recent years, moving up 42 spots since 2011.
But top managers at companies in the fields of scientific research and technology services saw their pay decrease by 4.2%.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
摩根士丹利的分析师乔纳斯认为，Model X的销量将会更加可观，但不是由于它的燃油经济性，而是它升级后的信息娱乐系统，以及独特的“鹰翼”式后车门。他还表示，如果Model X没有赢得所有的年度车型大奖，他会非常失望。他并不是唯一一个这样想的人。埃隆o穆斯克和其他很多祈祷特斯拉继续保持当前势头的人当然也会这样想。（财富中文网）
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
A modular microarray imaging system for highly specific COVID-19 antibody testing
Sometimes bosses suck. But if your boss sucks all the time and takes advantage of your time, it's time to find a new job.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Coming of age: in the modern banlieues of Paris and in San Francisco in the 1970s. These movies dramatize the harrowing, thrilling passage to womanhood with unsparing honesty and infinite compassion.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
“Through the second half of the 20th century we had this big dispersion of trade and economic activity around the world. All this specialisation meant exports rose faster than GDP,” Mr Williams says.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
6. China will also soonmake further announcements regarding affordable housing and more accessiblehealthcare. The country still needs 75 million more $75,000 housing unitsand it will begin breaking ground on them, in earnest, in 2014. Theseinvestments, particularly in health care, will effectively become self-funded,allowing average Chinese consumers to consider saving less, and spending more. It will drive longevity and years of productive employment.
Guangdong has cemented its position as the country's largest provincial economy for the 28th consecutive year, with its gross domestic product (GDP) exceeding 7.9 trillion yuan in 2016.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
除了跳舞，玛蒂还唱歌和表演，她已经出演了电视剧《美女上错身》(Drop Dead Diva)和《奥斯汀与艾丽》(Austin & Ally)。
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
You turn back the passage and want to find the Page 12, and then you smile.
A facile assay for rapid detection of COVID-19 antibodies
Song “The Sacred Land” (Sun Nan)
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
A cheery New Year hold lots of happiness for you!给你特别的祝福，愿新年带给你无边的幸福、如意。
In one example, Christie’s was offering the mid-18th-century canvas “Rebecca and Eliezer at the Well” by the Venetian artist Francesco Fontebasso at a low estimate of 120,000. The pleasant piece of rococo decoration had been bought at auction in 1990 for $286,000, according to Artnet. At the Dec. 8 sale it fell to a single telephone bid of 115,000, about $170,000, before fees. Investors do not expect to incur a loss of about 40 percent a quarter century after buying a Warhol or a Basquiat. Reselling an old master can be even harder when that painting has been languishing in a dealer’s gallery.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
This figure marks the highest rate of growth since 2011. As the total annual box office in China five years ago was only 10 billion yuan.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
“It suggests that people put more weight on what happened to themselves and less weight on other information that might be available,”Koudijs says. The more personally removed people are from an important event, the less it is to affect their appetite for risk.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
In addition, the top-ranking cities typically performed poorly in costs and culture and lifestyle. China's "cities of opportunity" continue to face challenges when it comes to building cities that satisfy the needs of the populace and provide a high quality of life.
Anti-HIV drug repurposing against SARS-CoV-2
The 43-year-old woman was placed on a 12-month good behaviour bond and banned from owning animals.
STEP 10: Even if you don't really fit the criteria, tell everyone you are a SOCIOPATH
In a statement given to the website Kotaku, Epic Games said the lawsuit was a result of Mr Rogers "filing a DMCA counterclaim to a takedown notice on a YouTube video that exposed and promoted Fortnite Battle Royale cheats and exploits."
Length-scale dependence of protein hydration-shell density
7、Bad body language habits
Heatwaves around the world, including one in India that led to more than 2,000 deaths and another in Iraq that saw the mercury top 50C, helped push temperatures 1C above pre-industrial levels for the first time, US and UK researchers said.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
The economy will grow 3% for the first time in 10 years
Hartz started Eventbrite, an online ticketing platform, with her now-husband Kevin in 2006. Since its founding, the company has raised $140 million from firms like Sequoia Capital and Tiger Global Management and reached $2 billion in gross ticket sales this September. Entrepreneurship forced Hartz to appreciate candid and collaborative conversations. "I had to learn how to ask for help," she says. "Everyone always thinks it's brave to go out alone, but I think it's even braver to put yourself out there in front of others, and to figure out how to work together."
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
According to Oliver Cooke, a financial-services recruiter at Selby Jennings in New York, banks have been stressing what they call “internal mobility”, or redeploying staff from one department to another. If a bank facing sluggish conditions in debt trading, for example, can convert a trader to a risk analyst or a compliance officer, it can keep people interested — and it can save a bundle on severance.
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Actor in a Comedy Series: Jeffrey Tambor, “Transparent”