Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

I may say "I'm terminating you because you didn't meet performance measures." I'm not going to say it's because you're a pain in the butt and piss people off every time you interact with them.
到底有哪些行业急需专业人才?说起这个问题,你可能怎么也不会想到“供应链管理”:这是一项复杂的幕后工作,负责将货物从甲地运到乙地,不仅要准时,还不能超支。
The winter holiday season will help thin the herd, but the true litmus test will be when a company can introduce a wearable that passes the “turnaround test,” Gilbert says—when a person walks a few steps from their front door and decides to turn around to retrieve a forgotten wearable device like they would a forgotten wallet, keys, or phone.
社交网络公司Facebook 、电子商务巨头亚马逊和玩具公司乐高则是品牌价值增幅最大的企业。
['k?pirait]
James Franco’s new movie about the making of The Room will make you belly-laugh, but its comedy is also deeper and richer than mere mockery.
His mother says he is a scapegoat. 'This company is in the process of attempting to sue a 14-year-old child,' she wrote in the letter which has been shared online.
facile(adj 易做到的;不花力气的;性格温和的)face,le乐:想让脸乐还不容易吗?Fac=face,ilit,ate吃:用脸吃饭还不容易吗?
[sin'si?li]
557,000 people were murdered across the world in 2001 alone. That number significantly dropped by 289,000 by 2008. The homocide rate is now in decline in 75% of nations.
China will continue to improve market environment and tap consumption potential while developing complementary cross-border industrial and value chain with countries along the Belt and Road Initiative in the next five years, according to Gao.
AFI TV Programs of the Year
adj. 社会的,社交的
2012年,电子烟开始流行,它们的工作原理是通过加热尼古丁的液体,模拟真实的烟。很多人认为电子烟是中国的制药商韩力发明的,他说梦到自己在烟雾缭绕的蒸气中快要窒息后,发明了电子烟。他的父亲死于吸烟引起的肺癌。他自己也是一个不折不扣的瘾君子,他曾尝试使用尼古丁贴片来戒烟,但失败了。
"In the aftermath of recessions, there's always a period of jobless recovery," says John Challenger, CEO of global outplacement firm Challenger Gray & Christmas. "We're certainly not optimistic about seeing much improvement in the unemployment rate in 2010."
In terms of salary three years after graduation, Germany leads the way for masters in management programmes, with three schools in the top four. Graduates of WHU Beisheim have the distinction of earning the highest salary, at $98,123 on average.
Be passionate about learning.
The strategy of Four comprehensives: Comprehensively building a moderately prosperous society, comprehensively driving reform to a deeper level, comprehensively governing the country in accordance with the law, and comprehensively enforcing strict Party discipline
“有个员工的父母跟公司联系,告诉我们说,他们的儿子辞职了。”
《好时光》
推动社会治理创新。
智能冰箱
[im'breis]
pandemic
THE SLAP (NBC, Feb. 12) Jon Robin Baitz and Lisa Cholodenko are producers of this adaptation of an Australian mini-series about the fallout from a momentary loss of control at a backyard birthday party. The impressive cast includes Peter Sarsgaard, Uma Thurman, Thandie Newton, Brian Cox and Melissa George (who also appeared in the original).


对于共同创始人哈勃,未来12个月的第一要务是强化Bigcommerce的内部科技人才队伍,提供能够帮助商户构建更紧密客户关系的服务。一个例子是提供数据,帮助店铺经理追踪“被丢弃的购物篮”,以及提供能够将浏览者转变为买家的交易。这能推动商户的月销售额迅速增加15%,他说。
从1970年到今天,世界各地的文盲减少了50%。
She had recently emerged as the right hand of her father, the former Prime Minister Nawaz Sharif. But corruption charges are clouding her rapid rise.


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

9.《老友记》中卡罗尔和苏珊的婚礼
Don’t cry for the WTO
The truth is, to shut our door to the outside world would not help China do its own things well, so China will continue to open to the outside world, with this opening-up being a gradual process.
Songs (Ping An, Xu Yina and Apusasa)

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

1. Discipline them: Of course disciplining our children is a given in any home. But we need to ask ourselves if we are disciplining our children properly? Who

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

斯卡曼德是个魔法生物研究学家。
中国的创新表现有所改善,在"创新质量"方面排名第17,这是个考量高校水平、科学出版物数量和国际专利申请量的指标。

Industry Kitchen的行政主厨布劳略?布耐对《城里城外》杂志表示,这份披萨的灵感来源于纽约的金融区,他将那里称为“堕落的缩影”。
vigor(n 精力;活力)
据IDC表示,2016年全球智能手机的出货量达到了14.7亿台,同比去年上涨2.3%。
相比之下,新兴市场出口的平均单价差不多自2012年中以来就一直呈同比下降趋势,2016年2月同比降幅达到16.4%。
你的阑尾终究可能不是一个无用的进化副产物。你的阑尾不像智齿那样,事实上它可能发挥着重要的生物学功能,恰好现在人类还没准备好放弃阑尾的这种功能。
On Nov. 24 and 25, Sotheby’s auctioned the collection of the fourth-generation Munich dealer Konrad Bernheimer, who owns the historic London gallery Colnaghi. Mr. Bernheimer, 65, has decided to scale down his operations. He is closing his Munich gallery, selling his grand Bavarian home, Marquartstein Castle, and is merging Colnaghi with a fellow London dealer, Coll & Cortes.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


基金经理眼里的2017年楼市:对房价持谨慎观点


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


He failed to do so and Presti smartly moved on while he could still recoup some value.
谢谢!
David said: ‘It was wonderful, you couldn’t fault it. It was perfection.’
Yang Yansui, director of the School of Public Policy And Management at Tsinghua University, said the four-trillion-pension balance was mostly in personal accounts, while the pay-as-you-go pension system was greatly challenged by dependency ratio.
这几年的实践可以证明,中国经济“硬着陆”论可以休矣。我们会长期保持中高速增长,并迈向中高端水平。
Hitachi Data Systems
Sohmers所推出的这个产品,可谓将高速运算能力和低能耗集为一体。Sohmers表示:“除了电子工程师外,我认为我还是一位创业者。我相信,我所作的工作,将会对整个世界产生重要的影响。”Sohmers在几年前从高中辍学,加入了Peter Thiel创立的创业加速器20 Under 20 Thiel Fellowship。2011年,在其他同龄人都在准备考大学的时候,Sohmers开始学习编程。他获得了10万美元的种子资金,并且跟随硅谷中一些著名的技术人才进行学习。Sohmers曾在麻省理工学院研究实验室进行工作和学习,研究从增强现实眼镜到激光通信系统的任何东西。也是在那里,他见到了REX的另一位联合创始人Kurt Keville。但是在他正式进入麻省理工学院研究室之前,他的父母似乎并不太支持他放弃学业。
4. 欧佩克的下一步行动。说到去年的油价暴跌,石油输出国组织(OPEC)起了很大作用(或者说要承担很大责任)。虽然许多评论人士都说欧佩克保持原油产量不变无关紧要,然而,仅油价在该组织11月份会议过后出现暴跌这一事实便充分证明了该组织对油价走势的影响力。目前,欧佩克——更确切地说是沙特——仍在坚持己见,毫无下调生产配额的迹象。2015年这一情况是否会得以延续,仍有待观察。
The 2017 grads of Tsinghua University earn an average salary of 9,065 yuan per month, according to the survey released by xinchou.cn, an internet salary survey and report provider.
库克决定通过增加派息和回购股票扩大其现金返还计划,帮助缓和了与维权投资者的关系。目前它总共向股东返还现金940亿美元。最终,库克以足够的坚忍抵挡住挑战,迎来了iPhone又一波增长捷报,以及从乔纳森?艾夫爵士(Sir Jonathan Ive)的设计室诞生的新产品。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

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在此次颁奖典礼上,麦肯锡全球董事总经理鲍达民(Dominic Barton)在典礼上还颁发了“布拉肯贠尔”青年商业作家奖(Bracken Bower Prize for young business writers),获奖者为克里斯托弗克利尔菲尔德(Christopher Clearfield)和安德拉什舠尔奇克(András Tilcsik)。他们计划出版的图书将会探索企业如何能够管控发生灾难性失败的风险。该奖项面向35岁以下作者,专门颁发给那些探讨增长所构成的挑战和机遇的商业图书计划,奖金为1.5万英镑。
Prices in popular emerging market debt and equity benchmarks have already fallen, while net inflows from overseas investors have dropped from $285bn in 2014 to $66bn this year, according to the Institute for International Finance, a group representing the world’s largest financial companies.
adj. 年长的,高级的,资深的,地位较高的
Businesses can benefit in other ways too. Craig Rollason, business analysis manager at National Grid, says he has improved his coaching skills by mentoring a Teach Firster.

Indeed, everyone from Jennifer Garner, to January Jones and Kylie Jenner have been photographed as they pick out their most spook-worthy pumpkins in time to send October out with a thrill.

  • Only the first three authors are listed, followed by "et al."
  • 工信部将再出新政 铝模板产业腾飞在即
  • 2016年家居行业需关注四件大事:行业“双洗牌”加剧需求“异质化”


你或许要很长时间才能实现工作与生活的平衡,但努力遵守这个清单,并将其作为创业的目标,将会产生不一样的效果。创业者如何看待所取得的进步?以及一家公司多快才能实现正常运营和实现收支平衡?遵循这些建议,你很快就能找到答案。
Caleb Rogers is one of two people facing legal action from gaming studio Epic Games for using cheat software to play the game Fortnite.

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