Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

“Yao represents the new wave of wealth creation by financial investments in China,” said Rupert Hoogewerf, who compiles the annual list.
n. 有毒物质
Online programmes appeal more to senior professional students than those who take full-time programmes. Participants on online MBAs are aged 34 on average compared to 28 for full-time participants. Online students are also more likely to seek a promotion following the course with their existing employer. While the majority of full-time MBA graduates (90 per cent) worked for different companies three years after graduation, only about 55 per cent of online graduates did so.
4. Your co-worker blabbed。
Brands vs the market
But the carriers are having a more difficult time over the winter holidays. About 30 percent of winter holiday flights were delayed in 2012, on top of significant delays in 2011 and 2010. You can check holiday flight statistics from the Transportation Department on its website.
Will Washington's tentative truce continue?
穆迪分析(Moody's Analytics)在报告发布之前表示:“由于大宗商品价格不断下跌,生产者价格仍将处于下行趋势。”
Premiered on Jan 29, the drama received 7 points out of 10 on the country's popular review website Douban.
The world's first flying bicycle flew on November 9, 1961, when Derek Pigott of the University of Southampton flew in a bicycle with an airplane-like body. It was called the Southampton University Man Powered Aircraft (sumpac). Derek furiously pedaled the air-bike to get it off the ground. It then flew 1.8 meters (about 6 ft) above the ground over a distance of 64 meters (210 ft). While the flight was short and slow, it still does not change the fact that it was the first bicycle to fly and at the same time, the first human-powered flight.
位于芬兰赫尔辛基的开发商Remedy Entertainment通过之前的作品《英雄本色》(Max Payne)和《心灵杀手》(Alan Wake)模糊了好莱坞和游戏之间的界限。如今,这家工作室将次世代的图像技术与紧张气氛和电视剧剧本结合了起来。故事设置在Riverport大学城,玩家将控制杰克o乔伊斯和贝斯o怀尔德。这两人原本是普通人,但在一次导致时间裂缝的意外中,他们获得了操纵时间的超能力。在游戏过程中,时间体系会随时崩溃,导致环境中的时间暂停、断续、倒流和冻结。玩家在游戏中会与帝王联盟(Monarch Corporation)展开对抗,喜欢《英雄本色》中子弹时刻的玩家,可以在放大时间因素的枪战中寻找新的战略。除了虚拟的故事情节,游戏还采用了定制的实景真人叙事模式,根据玩家的不同选择将产生不同的后果。
To Anita Eerland and Rolf Zwaan [THE NETHERLANDS] and Tulio Guadalupe [PERU, RUSSIA, and THE NETHERLANDS] for their study "Leaning to the Left Makes the Eiffel Tower Seem Smaller."
"China is Australia's most valuable tourism market, with the potential to be worth more than $13 billion by 2020."
中国中央和地方政府会对技术升级方面投入更多的经费。 包括现代化农业、运输、医疗等方面。这些积极的投资将会进一步提高中国生产和制造业的竞争能力。这将是一次国家行为,目的是为了推动提高产品质量和产品合格率以及以提升产品主导的全球竞争力。
Autonomous cars: Researchers are working on devices that will automatically park your car in a parking lot without you being in, or near, the car. It will also slip a note under the wipers of the car next to it with your phone number and insurance carrier in case of any scratches.
Not because I am happy to see the end of what was one of television’s smartest series, a pioneer of what is now generally accepted as the current golden age of small-screen serials.

2. Marc Faber's Doomsday warning on Bernanke's disastrous QE scheme

With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

凯莎与死亡金属之鹰乐队联合创作了《Let‘Em Talk》(《让他们说去吧》)这首流行朋克风格的歌曲,它以吉他原声为主导,是一首能够瞬间引爆全场的经典之作。
First, says Tom Kozenski, a supply-chain expert at consulting and training firm RedPrairie, most people still think of logistics -- if they think of it at all -- as a "non-sexy" field centered on boring, low-paid warehouse work.
11. MailChimp
We learned that nothing brings people together like the sun hiding behind the moon.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

5. Hong Kong, China-A junk boat set against the famous skyline might be the iconic shot of Hong Kong, but Lonely Planet picked the territory for its natural heritage miles away from Victoria Harbor.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 


Rounding out the top-performing sectors of 2014 was an unlikely pair: tech (+16%) and consumer staples (+13.2%)—the most aggressive and most defensive areas of the market, running side-by-side toward the finish line, with confounded spectators struggling to concoct a narrative for this. Why would the least cyclical sectors—healthcare, staples and utilities—lead the markets in a year in which unemployment plummeted and GDP growth gained momentum? Much to the chagrin of the pundit class, sometimes there are no satisfying answers. To quote Kurt Vonnegut:
n. 有价证券;担保;保证人;抵押物(security的
n. 舒适,安逸,安慰,慰藉
7. Hearing Aid
'So it's how do you square that circle? How do you remain true to the original creation and concept and yet at the same time not offend people in the 21st century?

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.

机构:一线楼市供不应求 房价或将继续上行


1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. 

33. RelaxLine. BellyBio. Accessed 28 August 2017.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.

The kitchen addition, about 40 feet long, was designed to be in keeping with the original house, with intricate ceiling woodwork and several colored-glass panels by Century Studios, a Minneapolis company that secured its glass from the Chicago manufacturer used by Frank Lloyd Wright. Stainless-steel appliances include a five-foot-wide range and a Sub-Zero refrigerator. The dining area opens to a back patio through 10-foot-tall glass doors.
William Leung, portfolio manager at Cohen & Steers, the US investment house with $4bn of assets exposed to Asia, agrees. He argues that speculative investment will be driven out of the market as prices fall. He adds that a trend in the industry towards alternative investments should mean that the price of real estate investment trusts rises even if the value of underlying assets grow more slowly. “We don’t think this correction will be so sharp,” he says.
*Guest Actor in a Drama Series: Hank Azaria, “Ray Donovan”
adj. 值得(做)的
Another indicator of bitcoin’s momentum is the number of mainstream businesses that accept it. In 2014, Microsoft MSFT -0.84% , PayPal, Dell, and Dish Network DISH 2.24% , among many others, announced they would accept bitcoin as payment for a range of products. Those companies joined companies such as Target (which accepts Gyft, which can be purchased with bitcoin),, and WordPress. Even the publisher of Fortune, Time Inc. TIME -0.40% ,began accepting the cryptocurrency for magazine subscriptions. Yahoo YHOO -1.02% also added bitcoin to its Yahoo Finance tracking site last year, lending the currency additional legitimacy, and Google Finance GOOG -1.30% quickly followed suit. “Adoption of bitcoin is becoming more commonplace, and we feel it is relevant to our industry and to our users,” a Yahoo spokesperson told CoinDesk. Don’t be at all surprised if Yahoo soon goes even bigger on bitcoin—whether by acquiring a bitcoin startup or some other announcement—as part of CEO Marissa Mayer’s ongoing effort to make the stalling search giant more hip.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.

Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

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The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the 这个报告没有谈到可能影响患病数量的原因,但是很多人,包括在野党的成员,归咎于政府一味缩减医疗健康成本预算。 to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.


When you are at work, you are supposed to be productive. Otherwise, it's a waste of your time and the company's money. If you are bored and surfing the web most of your work day, you may want to think about looking into job options where you'll get more stimulation and responsibilities.

  • Only the first three authors are listed, followed by "et al."
  • 楼市迎来诸多利好 价格其实在微跌深圳拼命涨
  • 深圳7月起禁用油漆能否引发全国各地响应?

Every year since 2003, Shanghai Ranking Consultancy has been releasing its rankings of the world top 500 universities based on third-party data.
In 2015, the number of migrant residents living in Shanghai dropped for the first time in the past 15 years, Shanghai Television reported Monday.

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